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REVIEW PAPER |
International Coordinating Centre for ADVANCE, Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
For reprint information contact: Anushka Patel, FRACP Tel: 61 2 9351 0031 Fax: 61 2 9351 0008 email: apatel{at}iih.usyd.edu.au Institute for International Health, University of Sydney, P.O. Box 576, Newtown, NSW 2042, Australia.
The prevalence of diabetes is increasing, particularly in developing regions of the world. The social and economic consequences of this disease and its complications are enormous. We discuss the scope and implications of the increasing burden of diabetes and describe the rationale and design of a new international study examining blood pressure lowering and glucose control interventions aimed at reducing the risk of vascular complications in people with type 2 diabetes. This study is the first large-scale randomized trial in diabetes to include participants from both lower- and higher-income regions of the world.
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