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Impact of Age on The Results of Coronary Artery Bypass Grafting

Department of Thoracic Surgery, Thoraxklinik, University of Heidelberg, Heidelberg, Germany
¹ Technologic Faculty, Neuroinformatic Groups, University of Bielefeld, Bielefeld, Germany
² Department of Cardiovascular and Thoracic Surgery, Heart Institute Lahr/Baden, Lahr/Schwarzwald, Germany
³ Department of Anesthesiological Research, University of Göttingen Göttingen, Germany

For reprint information contact: Amir Mortasawi, MD Tel: 49 6221 396 217 Fax: 49 6221 396 543 Email: amirmortasawi{at}yahoo.de Department of Thoracic Surgery, Thoraxklinik, University of Heidelberg, Amalienstr. 5, D-69126 Heidelberg, Germany.

As the average age of patients undergoing cardiac surgery is increasing, the effects of age on the incidence of postoperative complications and 30-day mortality after coronary artery bypass grafting were examined. The EuroSCORE and corresponding age-stripped EuroSCORE were calculated in 6,057 patients who underwent isolated coronary bypass between January 1996 and January 2002. Both EuroSCORE and age-stripped EuroSCORE exhibited a significant increase with age in the whole group of patients and in those who were alive 30 days after surgery. The 30-day mortality and the incidence of postoperative complications increased significantly with age. A significant age-dependent increase in EuroSCORE was found in patients who died within 30 days postoperatively, whereas no age dependence was observed in the age-stripped EuroSCORE. Univariate analysis showed diabetes mellitus and atrial fibrillation to be significant risk factors for 30-day mortality; atrial fibrillation was also found to significantly affect 30-day mortality on multivariate analysis. In view of the increasing co-morbidity and age-dependent organ changes in the elderly, specific preventive and therapeutic measures are needed in this group of patients undergoing cardiac surgery.

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