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Asian Cardiovasc Thorac Ann 2006;14:387-393
© 2006 Asia Publishing EXchange Ltd

ORIGINAL CONTRIBUTIONS

Evaluation of the Spatial Resolution with 1.5-4 Tesla in a Stenosis Model

Thomas Wittlinger, MD, Ivo Martinovic, MD1, Anton Moritz, MD, Sandro Romanzetti, MD2

Department of Thoracic and Cardiovascular Surgery, University Hospital, Frankfurt, Germany
1 Department of Heart Surgery, University Hospital, Marburg, Germany
2 Institute of Medicine, Research Center Jülich, Jülich, Germany

For reprint information contact: Thomas Wittlinger, MD Tel: 49 63 018 3315 Fax: 49 67 326 5370 Email: thomaswittlinger{at}t-online.de, Department of Thoracic and Cardiovascular Surgery, University Hospital, Theodor-Stern-Kai 7, Frankfurt 60590, Germany.

Since it was first described in the early 1990s, magnetic resonance coronary angiography has evolved into a promising noninvasive modality for imaging the coronary arteries. The aim of this study was to evaluate the detection accuracy and spatial resolution of vascular stenosis in contrast-enhanced 3-dimensional magnetic resonance angiography on a flow phantom. The examinations were performed with 1.5, 3, and 4 T whole-body imaging systems. For imaging at 4 T, we used a gradient-echo-multi-slice sequence. The system was flushed with gadopentetate dimeglumine contrast medium at flow rates of 40 and 60 mL·min–1. The accurate detection of in vitro stenoses was possible in segments of 0.4 mm in diameter at 4 T. The best results were obtained at a flow velocity of 40 mL·min–1 and a contrast medium concentration of 0.2 mmol·L–1. Contrast-enhanced high-field 3-dimensional magnetic resonance imaging provided a highly accurate evaluation of the degree of stenosis in this model. Exact evaluation of vessel diameters < 0.4 mm was not possible, even with 4 T. In vivo studies are necessary to overcome the current limitations in the visualization of small distal vessel segments.






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