Asian Annals
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Yoshihiro Oshima
Masahiro Yoshida
Masahiro Yamaguchi
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Asian Cardiovasc Thorac Ann 2007;15:376-380
© 2007 Asia Publishing EXchange Ltd

ORIGINAL CONTRIBUTIONS

Continuous Hemodiafiltration During Cardiopulmonary Bypass in Infants

Naoki Yoshimura, MD, Yoshihiro Oshima, MD, Masahiro Yoshida, MD, Hirohisa Murakami, MD, Hironori Matsuhisa, MD, Masahiro Yamaguchi, MD

Department of Cardiothoracic Surgery, Kobe Children’s Hospital, Kobe, Japan

For reprint information contact: Naoki Yoshimura, MD, Tel: 81 76 434 7330, Fax: 81 76 434 5032, Email: ynaoki{at}med.u-toyama.ac.jp, First Department of Surgery, University of Toyama, School of Medicine, 2630, Sugitani, Toyama 930-0194, Japan.

The homologous blood prime in cardiopulmonary bypass circuits contributes a significant electrolyte and metabolite load in small infants. The efficacy of hemofiltration and continuous hemodiafiltration of the blood prime in preventing metabolic disturbances in small infants was compared in two groups of 60 patients each. Blood pH, base excess, and calcium concentrations decreased during cardiopulmonary bypass in the hemofiltration group. The acid-base balance was well preserved during cardiopulmonary bypass by continuous hemodiafiltration. This therapeutic strategy may confer an advantage in maintaining more physiological conditions during cardiopulmonary bypass in small infants.






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