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Left Ventricular Hypertrophy and Remodeling after Aortic Valve Replacement

Cardiovascular Surgery Department,
¹ Cardiology Department, Kent Hospital, Izmir, Turkey

For reprint information contact: Hikmet Iyem, MD, Tel: 90 232 386 7070, Fax: 90 232 386 7071, Email: hikmeti{at}hotmail.com, Kent Hastanesi Kalp ve Damar Cerrahi bölümü, Cigli Izmir 35580, Turkey.

Left ventricular geometric remodeling and regression of hypertrophy were assessed after aortic valve replacement with a mechanical prosthesis in 37 patients with aortic stenosis and 39 with aortic insufficiency, aged 54.2 ± 14.3 and 52.6 ± 16.6 years, respectively. The follow-up period was 2 years. In patients with aortic insufficiency, ejection fraction increased from 54.4 ± 3.5 preoperatively to 59.6 ± 3.4 after 6 months and 61.7 ± 2.7 after 2 years. In patients with aortic stenosis, ejection fraction increased from 56.6 ± 5.1 preoperatively to 63.9 ± 4.4 after 6 months and 71.7 ± 4.1 after 2 years. Geometric remodeling, regression of hypertrophy, and increased ejection fraction of the left ventricle were similar in both groups at 6 months after surgery, but after 2 years of follow-up, greater improvement was found in patients who had undergone valve replacement for aortic stenosis.