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Acute Fatal Post-CABG Low Dose Amiodarone Lung Toxicity

Cardiac Surgery Department
¹ Pathology Department, Evaggelismos General Hospital Athens, Greece

For reprint information contact: Panagiotis Hountis, MD, Tel: 30 21 0213 3487, Fax: 30 21 0213 3487, Email: panos_hountis{at}hotmail.com, Evaggelismos General Hospital, Veikou 9-11, 11146 Athens, Greece.

Amiodarone is one of the commonly used anti-arrhythmic agents with well-recognized chronic pulmonary toxicity. We present our experience of a patient with a fatal outcome after coronary artery bypass grafting and a short course of amiodarone treatment with a low total cumulative dose for the treatment of postoperative atrial fibrillation. Necropsy revealed diffuse pulmonary damage due to acute amiodarone lung toxicity.