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Renal Outcome Following On- and Off-Pump Coronary Artery Bypass Graft Surgery

Division of Cardiothoracic Anesthesia
¹ Division of Cardiothoracic Surgery
² Department of Community Health, Heart and Lung Center, Hospital University Kebangsaan Malaysia, Kuala Lumpur, Malaysia

For reprint information contact: Joanna SM Ooi , MMed(Anaes) Tel: 60 3 9145 5555 Ext. 5852 Fax: 60 3 9173 7826 Email: joanna{at}mail.hukm.ukm.my, Department of Anaesthesiology & Intensive Care, Faculty of Medicine, University Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras 56000, Kuala Lumpur, Malaysia.

A prospective study was carried out to compare the outcomes of patients with preexisting non-dialysis-dependent renal dysfunction who underwent coronary artery bypass grafting with or without cardiopulmonary bypass. Elective off-pump coronary artery bypass was performed in 29 patients with renal dysfunction. Their results were compared with those of a similar group of 35 patients who underwent the conventional on-pump coronary artery grafting. There was a significant deterioration in creatinine clearance in the on-pump group on days 1, 2, and 4 after surgery, while creatinine clearance in the off-pump group remained close to the baseline level. Both groups had improved to the preoperative creatinine clearance values on follow-up at 4 weeks. It was concluded that off-pump surgery provided better renal protection than the conventional on-pump technique in patients with preexisting non-dialysis-dependent renal dysfunction.

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				G. Lema Renal Outcome Following On- and Off-pump Coronary Artery Bypass Graft Surgery: Few Patients, Cautious Conclusions Asian Cardiovasc Thorac Ann, August 1, 2009; 17(4): 440 - 441. [Full Text] [PDF]