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ORIGINAL ARTICLE

Short- and Long-Term Results of Lung Resection for Cancer in Octogenarians

Luca Voltolini, MD, Cristian Rapicetta, MD, Tommaso Ligabue, MD1, Luca Luzzi, MD, Valerio Scala, MD, Giuseppe Gotti, MD

Thoracic Surgery Unit, University Hospital of Siena, Siena, Italy
1 Thoracic Surgery Unit, Spedali Civili Riuniti, Brescia, Italy

Cristian Rapicetta, MD, Tel: +39 0577 586 140; Fax: +39 0577 586 140; Email: rapsody2000{at}alice.it, Thoracic Surgery Unit, University Hospital of Sienna, Viale Bracci 1 – 53100, Siena, Italy.

ABSTRACT

To analyze short- and long-term results of surgery in octogenarians, we reviewed data of 96 consecutive patients aged 80 years or more who were operated on for non-small-cell lung carcinoma from 1990 to 2005. Risk factors for complications, perioperative mortality, and long-term survival were assessed by univariate and multivariate analysis. Major complications developed in 17 (17.7%) patients, leading to death in 9 (9.4%) of them. Resection of more than 1 lobe, cardiorespiratory comorbidity, PaO2 < 75 mm Hg, and CO diffusion capacity <60% were predictive of major complications; extended resection was also predictive of 30-day mortality. The overall 5-year survival rate was 38%, with a significant difference between stage I/II and stage III. In multivariate analysis only pathological stage was related to long-term survival. Surgery is feasible for octogenarians, and even patients in stage II can achieve remarkable survival.

Key Words: Octogenarians • Carcinoma • Non-Small-Cell Lung • Pneumonectomy • Postoperative Complications • Survival Rate

Asian Cardiovasc Thorac Ann 2009; 17:147-152
© 2009 by SAGE Publications
DOI: 10.1177/0218492309103295




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