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Reserpine-Induced Complete Heart Block

Department of Cardiology Postgraduate Institute of Medical Education and Research Chandigarh, India

For reprint information contact: Mandeep Singh, DM Department of Cardiology Postgraduate Institute of Medical Education and Research Chandigarh 160012, India Tel:91 172 54 1032 Fax:91 172 54 0401

Reserpine is an adrenergic neuron blocking agent that acts by depleting the stores of catecholamines. Its use as an antihypertensive has declined recently because of frequent undesirable side-effects. The side-effects are primarily extracardiac and occur at high dosages. Cardiovascular side-effects are rare and include a decrease in atrioventricular conduction, potentiation of digitalis toxicity, and possible precipitation of ventricular ectopics. We report a case of reseprine-induced complete heart block requiring a temporary pacemaker for a few days.