HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Moghe, G. Articles by Vyas, J. Search for Related Content PubMed Articles by Moghe, G. Articles by Vyas, J.

Atypical Carcinoid Tumors of Lung: Clinicopathologic Study of Six Cases

Department of Pathology 1 Department of Surgery Tata Memorial Hospital Mumbai, India

For reprint information contact: Nirmala A Jambhekar, MD Tel: 91 22 414 6750 Fax: 91 22 414 6937 email: medimail{at}tmc.ernet.in Department of Pathology, Tata Memorial Hospital, Dr. Ernest Borges Road, Parel, Mumbai 400012, India.

This retrospective study of 6 cases of atypical carcinoid tumor was carried out to highlight their clinicopathological features and behavior. All patients were over 40 years of age and were treated by surgical excision of the tumor. Four tumors were central and 2 were peripherally located in the lung. Grossly, the tumors were large with spotted areas of necrosis. Microscopically, all tumors had a typical carcinoid pattern with spotted areas of necrosis and mitotic activity in the range of 2 to 5 per 10 high-power fields. On immunohistochemistry, the tumors were positive for neuron-specific enolase and cytokeratin. Follow-up ranging from 1 to 5 years was available in 4 patients; 2 are currently alive, 1 with local recurrence and distant metastasis one year postoperatively, the other with no disease after 5 years. Two patients died; one had a local recurrence at 2 years and the other had liver metastasis at 3 years.