HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Guy J Fradet Samuel V Lichtenstein Robert T Miyagishima Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Jamieson, W. E. Articles by Miyagishima, R. T Search for Related Content PubMed Articles by Jamieson, W. E. Articles by Miyagishima, R. T

Bioprostheses and Mechanical Prostheses Predictors of Performance

Department of Surgery Faculty of Medicine University of British Columbia Vancouver, British Columbia, Canada

For reprint information contact: WR Eric Jamieson, MD Tel: 1 604 806 8383 Fax: 1 604 806 8384 St. Paul's Hospital, 1081 Burrard St., 331–332 Burrard Building, Vancouver, BC V6Z 1Y6, Canada.

From 1975 to 1995, 4200 patients had bioprosthetic valve replacements (2240 aortic, 1607 mitral, 353 multiple) and 2038 had mechanical valve replacements (747 aortic, 928 mitral, 363 multiple). Freedom from major thromboembolism or both major thromboembolism and hemorrhage for aortic and mitral valve replacement at 15 years was significantly greater for bioprostheses than mechanical prostheses. Freedom from valve-related mortality and reoperation for both aortic and mitral valve replacements was the same for bioprostheses and mechanical prostheses. Advancing age increased overall mortality (all positions), valve-related mortality (aortic, mitral), major thromboembolism (aortic), thromboembolism and hemorrhage (aortic, mitral) but decreased reoperation (all positions). Coronary artery bypass grafting increased overall mortality (aortic, mitral) but not valve-related mortality, and it decreased reoperation rate (aortic, mitral). Overall mortality was not influenced by valve type in aortic or multiple valve replacement but it was decreased by bioprostheses in mitral valve replacement. Valve type did not influence valve-related mortality (all positions). Mechanical valves decreased reoperation only for aortic valve replacement but they increased major thromboembolism with and without hemorrhage for both aortic and mitral replacements. There is support for bioprostheses in aortic valve replacement and mechanical prostheses in mitral valve replacement but for neither in multiple valve replacements.

This article has been cited by other articles:

				K. Prasongsukarn, W. E. Jamieson, E. Germann, F. Chan, and S. V Lichtenstein Aortic and Mitral Prosthetic Valve Replacement in Age Groups 61 65 & 66 70 Years Asian Cardiovasc Thorac Ann, April 1, 2007; 15(2): 127 - 133. [Abstract] [Full Text] [PDF]