HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Garg, N. Articles by Sinha, N. Search for Related Content PubMed Articles by Garg, N. Articles by Sinha, N.

Role of Pretransplant Arteriography in Diabetic End-Stage Renal Disease

Department of Cardiology 1 Department of Nephrology Sanjay Gandhi Post-Graduate Institute of Medical Sciences Lucknow, India

For reprint information contact: Nakul Sinha, MD, DM Tel: 91 522 44 0700 Ext. 2223 Fax: 91 522 44 0973 email: nsinha{at}sgpgi.ac.in Department of Cardiology, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India.

Diabetic renal transplant candidates have a high prevalence of obstructive coronary artery disease that is a major cause of morbidity and mortality. This study sought to stratify the risk for renal transplantation by correlating noninvasive tests with arteriographic findings. Fifty-two diabetics (46 males, 6 females) with end-stage renal disease were evaluated noninvasively and by coronary arteriography. The mean age was 46 ± 6 years. Twenty-five patients (48%) had noninvasive evidence of coronary artery disease (angina in 10, old myocardial infarction on electrocardiogram in 6, ST-T changes in 8, regional wall motion abnormality on echocardiography in 8, positive dobutamine echocardiogram in 4, and positive dipyridamole thallium tests in 13). Obstructive coronary artery disease was demonstrated by arteriography in 27 (51.9%). Concordance between noninvasive findings and arteriography was 65.3%. Obstructive coronary disease was present in 66.7% of those with 2 noninvasive indications, in all with more than 2 indications, and in all cases of regional wall motion abnormality. Thus, more than 2 positive noninvasive parameters or wall motion abnormality on an echocardiogram were highly predictive of coronary disease.