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Fifteen-Year Experience With Shanghai Disc Valve Prosthesis

Department of Cardiothoracic Surgery Zhujiang Hospital, First Military Medical University Guangzhou, Guangdong People's Republic of China
For reprint information contact: Zhu Ping, MD Tel: 86 20 8514 3591 Fax: 86 20 8431 8440 email: Zhuyiwen{at}public.guangzhou.gd.cn Department of Cardiothoracic Surgery, Zhujiang Hospital, Zhuangtou, Haizhu District, Guangzhou, Guangdong 510282, People's Republic of China.

Between 1983 and 1998, 168 Shanghai prosthetic heart valves were implanted in 122 patients (57 males, 65 females) aged 14 to 57 years (mean, 34 years). There were 69 mitral, 7 aortic, and 46 double valve replacements. Early mortality in each group was 8.7%, 14.3%, and 6.5%, respectively. Mean follow-up was 7.9 years (87.5% complete). There were 7 late deaths (5.7%); 2 in the mitral group, 5 in the double valve group. Five late deaths were considered valve-related. The 5-year actuarial survival rates were 96.8% for mitral, 100% for aortic, and 88% for double valve replacement. Preoperatively, 77.9% of patients were in New York Heart Association functional class III or IV, whereas postoperatively, 90.2% were in class I or II. No structural failure was observed. There were 3 cases of systemic and cerebral embolism, and 2 cases of valve thrombosis in patients who had ceased taking anticoagulants. Hemorrhage was the most frequent complication; 1 of 6 events was fatal. The very affordable Shanghai valve provided good hemodynamic performance with low thrombogenicity in patients receiving anticoagulants.